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PROSCIS-B - The CSB Prospective Stroke Cohort

This experiment investigates the process of stroke and the risk of sequelae.
More information/project description

Research Group Endres
Research Group Siegerink

Project Description

Background

  • Risk of stroke recurrence after stroke is substantial
  • Patterns of risk transition between subtypes of vascular diseases remain unclear
  • Long-term data on stroke sequelae (e.g. depression, cognitive decline) are scarce

Aims and Objectives

  • Determine long-term patterns of vascular disease risk up to 3 years after index event
  • Identify natural course of stroke associates outcomes and comorbidities
  • Provide external validation of estimates from independent datasets

Methods

  • Established cohort methodology, including initial and follow up assessments
  • Recruitment of patients with first ever stroke to the cohort
  • Annual follow up of patients up to 3 years after stroke
  • Mapping of vascular disease risk, comorbidities and outcomes
  • External validation of derived estimates  

Status

  • Started: February 2010

Coordination

  • Prof. Matthias Endres, M.D.
  • Thomas Liman, M.D.

PI

  • Prof. Matthias Endres, M.D.
  • Thomas Liman, M.D.

Registration

  • clinicaltrials.org/NCT01363856
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