PROSCIS-B – The CSB Prospective Stroke Cohort

Project Description

Background

• Risk of stroke recurrence after stroke is substantial
• Patterns of risk transition between subtypes of vascular diseases remain unclear
• Long-term data on stroke sequelae (e.g. depression, cognitive decline) are scarce

Aims and Objectives

• Determine long-term patterns of vascular disease risk up to 3 years after index event
• Identify natural course of stroke associates outcomes and comorbidities
• Provide external validation of estimates from independent datasets

Methods

• Established cohort methodology, including initial and follow up assessments
• Recruitment of patients with first ever stroke to the cohort
• Annual follow up of patients up to 3 years after stroke
• Mapping of vascular disease risk, comorbidities and outcomes
• External validation of derived estimates  

Status

• Started: February 2010

Coordination

• Prof. Matthias Endres, M.D.
• Thomas Liman, M.D.

PI

• Prof. Matthias Endres, M.D.
• Thomas Liman, M.D.

Registration

• clinicaltrials.org/NCT01363856