Prevent complications

AF Registry - Berlin Cohort Study on Oral Anticoagulation in Patients with Atrial Fibrillation and Acute Ischemic Stroke

The study is an Investigator-initiated, prospective, multi-centre cohort study using the established collaborative group of the Berlin Stroke Register (BSR) to gather data on eligible stroke patients and to investigate in the city of Berlin about the secondary prevention for stroke and the adherence regarding the prescriptions in patients with known atrial fibrillation and ischemic stroke.
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Prevent complications

AMINO-Stroke - Effect of Essential Amino Acids on Muscle Size and Strength in Patients with Acute Ischemic Stroke during Rehabilitation

This study assess the effect of essential amino acid supplementation on muscle wasting, muscle strength, mobility, and self-dependence in patients during rehabilitation after acute stroke.
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Prevent complications

Brain Gut Interaction

This project explores the following hypotheses

  • Stroke changes the gut microbiome
  • The gut microbiome affects outcome after stroke
  • Gut microbiome impacts on outcome after CNS lesion via a) effects on the immune system, including costimulation by bacterial products; b) direct humoral/metabolic signaling; and c) effects on enteral nervous system.

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Prevent complications

Brain Immune Interaction

Given the experimental and clinical evidence that CNS injury-induced immunodepression syndrome (CIDS) fosters post-stroke infection and that infections might worsen stroke outcome, immunomodulatory therapies to reconstitute antimicrobial host immune defenses may provide a new approach to improve stroke outcome.
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Prevent complications

CORONA-IS

The primary objective of the CORONA-IS study (CardiOmyocyte injuRy follOwing Acute Ischemic Stroke) is to explore the developmental mechanisms of stroke-associated, acute myocardial damage in an interdisciplinary approach.
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Prevent complications

HEBRAS – Heart and Brain interaction in Acute Stroke

This prospective observational study is examining whether an enhanced MRI investigation leads to a significant increase of the findings regarding the cause of stroke.
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Prevent complications

INSPiRE-TMS

INSPiRE-TMS stands for Intensified Secondary Prevention intending a Reduction of vascular re-events in patients with TIA or Minor Stroke). Implementation of a supported secondary prevention program in patients with minor stroke or TIA and evaluation in a randomized controlled trial.
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Prevent complications

MAS – Managing Aftercare for Stroke

This observational study is designed to evaluate remaining deficits of patients who suffered a stroke months and years ago.
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Prevent complications

MonDAFIS – Impact of standardized MONitoring for Detection of Atrial Fibrillation in Ischemic Stroke

Investigator-initiated, prospective, randomized, open-label, multi-center trial with two parallel groups. Randomization of patients happened 1:1 into one group that received standard care and one group that received standard care plus additional Holter ECG monitoring.
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Prevent complications

Neuropsychiatric disorders and stroke

We seek to make further inroads into understanding the complex interaction between depression and brain ischemia at a mechanistic level.
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