[Translate to English:] Jessica L. Rohmann

Research group Rohmann

Jessica L. Rohmann, M.Sc, PhD candidate
Charité, Center for Stroke Research Berlin
Research group Neuroepidemiology
jessica.rohmann(at)charite.de

Profile

Research in the Neuroepidemiology Group focuses on the development and application of modern epidemiological and statistical methods in the context of stroke and other neurological diseases. Our research projects focus on the application of causal inference methods and clinical risk prediction modeling, as well as methods work at the intersection of these domains. Our diverse breadth of applied projects in medicine and population health illustrate how methodological projects often transcend traditional discipline boundaries. Currently, our clinical focus areas include headache disorders and neurovascular outcomes, hypercoagulability, short- and long-term outcomes after stroke, sex- and gender aspects in neurovascular disease, and the analysis of neurological disease registry data.

The Neuroepidemiology Group further contributes methodological expertise to studies at the Center for Stroke Research as well as to numerous national and international collaborations. Our group values reproducibility, transparency, and quality of methodological reporting in research. We actively promote the use of modern causal inference tools, such as directed acyclic graphs, in applied research. We advocate for these aspects within the Charité through our involvement in training Master’s and doctoral students as well as early-career researchers. For example, our group members are active in the Health Data Sciences PhD Program and the Peerspectives peer-review training initiative (in collaboration with the BMJ). Outreach activities, such as the Berlin Epidemiological Methods Colloquium (BEMC), promote continuing education on these topics and serve to connect the Berlin community of methodological enthusiasts at-large.

We closely collaborate with the Causal methOds and NeuroVascular Epidemiology Research Group (CONVERGE) at the Institute of Public Health at the Charité and with Bob Siegerink, PhD (former CSB group leader) at the Department of Clinical Epidemiology at the Leiden University Medical Center.

 

List of Publications / Charité Research Data Base

Google Scholar

ORCID

Selected Publications

Coagulation factor XII, XI, and VIII activity levels and secondary events after first ischemic stroke.
Rohmann JL, Huo S, Sperber PS, Piper SK, Rosendaal FR, Heuschmann PU, et al.

J Thromb Haemost. 2020 Sep 16. dx.doi.org/10.1111/jth.15092.


PMID: 32935900

Directed acyclic graphs and causal thinking in clinical risk prediction modeling.
Piccininni M, Konigorski S, Rohmann JL, Kurth T.

BMC Med Res Methodol. 2020 Jul 2;20(1):179. dx.doi.org/10.1186/s12874-020-01058-z.


PMID: 32615926

Parallel pandemic: The crush of covid-19 publications tests the capacity of scientific publishing.
Kurth T, Piccininni M, Loder EW, Rohmann JL.
BMJ Opinion. 2020 May 26.

Blockchain-based innovations for population-based registries for rare neurodegenerative diseases.
Piccininni M, Rohmann JL, Logroscino G, Kurth T.

Frontiers in Blockchain. 2020;3:20. doi.org/10.3389/fbloc.2020.00020

 

Performance of risk prediction scores for cardiovascular mortality in older persons: External validation of the SCORE OP and appraisal.
Piccininni M*, Rohmann JL*, Huscher D, Mielke N, Ebert N, Logroscino G, et al.

PLoS One. 2020 Apr 9;15(4):e0231097. dx.doi.org/10.1371/journal.pone.0231097.


PMID: 32271825
(*shared authorship)

Migraine, headache, and mortality in women: a cohort study.
Rohmann JL, Rist PM, Buring JE, Kurth T.

J Headache Pain. 2020 Mar 17;21(1):27. dx.doi.org/10.1186/s10194-020-01091-9.


PMID: 32183686

Serum Anti-NMDA (N-Methyl-D-Aspartate)-Receptor Antibodies and Long-Term Clinical Outcome After Stroke (PROSCIS-B).
Sperber PS, Siegerink B, Huo S, Rohmann JL, Piper SK, Prüss H, et al.

Stroke. 2019 Sep 17;STROKEAHA119026100. dx.doi.org/10.1161/STROKEAHA.119.026100.


PMID: 31526121

Genetic determinants of activity and antigen levels of contact system factors.
Rohmann JL, de Haan HG, Algra A, Vossen CY, Rosendaal FR, Siegerink B

J Thromb Haemost. 2019 Jan;17(1):157–68. dx.doi.org/10.1111/jth.14307.


PMID: 30288888

Further Projects

Protect brain
Prevent complications

B-SPATIAL - Registry for quality assurance in stroke therapyin Berlin 
Stroke is a leading cause of death and disability. However, improving diagnostics and treatments such as thrombolysis and endovascular therapy have substantially reduced the burden of this disease. The B-SPATIAL registry (Berlin – Specific Acute Therapy in Ischemic or hemorrhagic stroke with Long-term follow–up) captures the processes during acute care of stroke patients and provides a unique opportunity to assess their effects on functional outcome.

Methodological research

Our team helps other research groups at the CSB to properly design and analyze their studies. Through their questions we sometimes stumble upon new methods and statistics that might be useful in stroke research. New research projects, where we combine knowledge from clinical and pre-clinical sciences are the result. This includes projects on

  • The use of non-parametric statistical methods for ordinal data analyses in stroke trials
  • The use of telephone interviews to establish functional outcome after stroke
  • The impact of misclassification on different types of confounding adjustment/elimination strategies
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