Research Group Endres

Prof. Matthias Endres, M.D.
Charité, Department of Neurology
Interdisciplinary stroke research
matthias.endres(at)charite.de

Most Important Projects

Prevent complications

AF Registry - Berlin Cohort Study on Oral Anticoagulation in Patients with Atrial Fibrillation and Acute Ischemic Stroke

The study is an Investigator-initiated, prospective, multi-centre cohort study using the established collaborative group of the Berlin Stroke Register (BSR) to gather data on eligible stroke patients and to investigate in the city of Berlin about the secondary prevention for stroke and the adherence regarding the prescriptions in patients with known atrial fibrillation and ischemic stroke.
More information/project description

Prevent complications

CORONA-IS

The primary objective of the CORONA-IS study (CardiOmyocyte injuRy follOwing Acute Ischemic Stroke) is to explore the developmental mechanisms of stroke-associated, acute myocardial damage in an interdisciplinary approach.
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Prevent complications

MonDAFIS – Impact of standardized MONitoring for Detection of Atrial Fibrillation in Ischemic Stroke

Investigator-initiated, prospective, randomized, open-label, multi-center trial with two parallel groups. Randomization of patients happened 1:1 into one group that received standard care and one group that received standard care plus additional Holter ECG monitoring.
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Prevent complications

Neuropsychiatric disorders and stroke

We seek to make further inroads into understanding the complex interaction between depression and brain ischemia at a mechanistic level.
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Prevent complications

PRAISE

The primary goal of the PRAISE (Prediction of acute coronary syndrome in acute ischemic stroke) study is to develop a diagnostic algorithm that allows the prediction of acute coronary syndrome in stroke patients.
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Protect brain

PROSCIS-B – The CSB Prospective Stroke Cohort

This experiment investigates the process of stroke and the risk of sequelae.
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Selected Publications

TRELAS Study Group: Coronary Angiographic Findings in Acute Ischemic Stroke Patients With Elevated Cardiac Troponin: The Troponin Elevation in Acute Ischemic Stroke (TRELAS) Study.
Mochmann, H.C., Scheitz, J.F., Petzold, G.C., Haeusler, K.G., Audebert, H.J., Laufs, U., Schneider, C., Landmesser, U., Werner, N., Endres, M., Witzenbichler, B., Nolte, C.H., TRELAS Study Group.
Circulation. 2016;133(13):1264-71.

Functional outcomes of pre-hospital thrombolysis in a mobile stroke treatment unit compared with conventional care: an observational registry study.
Kunz, A., Ebinger, M., Geisler, F., Rozanski, M., Waldschmidt, C., Weber, J.E., Wendt, M., Winter, B., Zieschang, K., Fiebach, J.B., Villringer, K., Erdur, H., Scheitz, J.F., Tütüncü, S., Bollweg, K., Grittner, U., Kaczmarek, S., Endres, M., Nolte, C.H., Audebert, H.J.
Lancet Neurol. 2016;15(10):1035-43.

Impact of standardized MONitoring for Detection of Atrial Fibrillation in Ischemic Stroke (MonDAFIS): Rationale and design of a prospective randomized multicenter study.
Haeusler, K.G., Kirchhof, P., Heuschmann, P.U., Laufs, U., Busse, O., Kunze, C., Thomalla, G., Nabavi, D.G., Röther, J., Veltkamp, R., Endres, M.
Am Heart J. 2016;172:19-25.

Team

Scientific Staff

  • PD Dr. med. Wolfgang Böhmerle
  • Prof. Dr. med. Dr. phil. Martin Ebinger (Gast)
  • Dr. med. Julius Emmrich
  • PD Dr. med. Karen Gertz
  • Dr. med. Petra Hühnchen
  • Dr. rer. nat. Friederike Klempin (assoziiert)
  • Dr. med. Samuel Knauss
  • Prof. Dr. med. Golo Kronenberg (Gast)
  • Dr. rer. nat. Nielsen Lagumersindez Denis
  • PD Dr. med. Thomas Liman
  • Dr. med. Alexander Nave
  • Dr. med. Vincent Prinz (assoziiert)
  • PD Dr. med. Jan Scheitz (assoziiert)
  • Christian Schinke
  • Johanna Schöner
  • Ria Uhlemann, Dipl.-Biol. PhD

Students

  • Carolin Albrecht
  • Adam David Dordevic
  • Burcu Ersoy
  • Paul Fischer
  • Lorena Ginesta Roque
  • Kerstin Hohgräwe
  • Michael Levitanus
  • Antonia van Kampen
  • Johannes Kern
  • Stephanie Wegner

Technical Staff

  • Stefanie Balz
  • Renate Franke
  • Bettina Herrmann
  • Melanie Kroh
  • Petra Loge 

Research Fields

  • Post stroke depression
  • Endothelial function in cerebrovascular diseases
  • Inflammation and stroke
  • Cognitive deficits after critical illness
  • Mechanisms of Ischemic Tolerance
  • Neurotoxicology
  • Regeneration after stroke
  • Risk factors
  • Telemedicine
  • Vascular mechanisms of stroke protection
  • Cerebral haemorrhage

Find more details about the research fields on the ExpNeuro website.

Cooperations

International

  • C. Ayata, Boston, USA
  • B.E. Ehrlich, New Haven, USA
  • M.A. Moskowitz, Boston, USA
  • J.C. Baron, Paris, France
  • E. Dejana, Milan, Italy
  • M. Elkind, New York, USA


National

  • M. Götz, Neuherberg/München
  • Tim Hagenacker, Essen
  • Lucie Heinzerling, Erlangen
  • P.U. Heuschmann, Würzburg
  • Helmar Lehmann, Köln
  • G. Kempermann, Dresden
  • U. Laufs, Homburg Saar
  • Mathias V. Schmidt
  • J. Schulz, Aachen


Berlin Area

  • Michael Bader, MDC
  • Holger Gerhardt, MDC
  • F. Heppner, Charité
  • H. Kettenmann, MDC
  • U. Kintscher, Charité
  • T. Kurth, Charité
  • D. Schmitz, Charité
  • Werner Stenzel, Charité
  • M. Taupitz, Charité
  • P. Vajkoczy, Charité
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