Research Group Endres

Professor Matthias Endres, M.D.
Charité, Department of Neurology
Interdisciplinary stroke research
matthias.endres(at)charite.de

Most Important Projects

Prevent complications

MonDAFIS - Impact of standardized MONitoring for Detection of Atrial Fibrillation in Ischemic Stroke

Investigator-initiated, prospective, randomized, open-label, multi-center trial with two parallel groups. Randomization of patients happens 1:1 into one group that receives standard care and one group that receives standard care plus additional Holter ECG monitoring.
More information/project description

Prevent complications

Poststroke Depression

We seek to make further inroads into understanding the complex interaction between depression and brain ischemia at a mechanistic level.
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Prevent complications

PRAISE

The primary goal of the PRAISE study is to develop a diagnostic algorithm that allows the prediction of acute coronary syndrome in stroke patients.
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Protect brain

PROSCIS-B - The CSB Prospective Stroke Cohort

This experiment investigates the process of stroke and the risk of sequelae.
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Prevent complications

TRELAS - TRoponin ELevation in Acute Stroke

In 5-34% of patients with acute ischemic stroke increased troponins are found. Regarding the optimal care for these patients, there is little evidence.
More information/project description

Selected Publications

TRELAS Study Group: Coronary Angiographic Findings in Acute Ischemic Stroke Patients With Elevated Cardiac Troponin: The Troponin Elevation in Acute Ischemic Stroke (TRELAS) Study.
Mochmann, H.C., Scheitz, J.F., Petzold, G.C., Haeusler, K.G., Audebert, H.J., Laufs, U., Schneider, C., Landmesser, U., Werner, N., Endres, M., Witzenbichler, B., Nolte, C.H., TRELAS Study Group.
Circulation. 2016;133(13):1264-71.

Functional outcomes of pre-hospital thrombolysis in a mobile stroke treatment unit compared with conventional care: an observational registry study.
Kunz, A., Ebinger, M., Geisler, F., Rozanski, M., Waldschmidt, C., Weber, J.E., Wendt, M., Winter, B., Zieschang, K., Fiebach, J.B., Villringer, K., Erdur, H., Scheitz, J.F., Tütüncü, S., Bollweg, K., Grittner, U., Kaczmarek, S., Endres, M., Nolte, C.H., Audebert, H.J.
Lancet Neurol. 2016;15(10):1035-43.

Impact of standardized MONitoring for Detection of Atrial Fibrillation in Ischemic Stroke (MonDAFIS): Rationale and design of a prospective randomized multicenter study.
Haeusler, K.G., Kirchhof, P., Heuschmann, P.U., Laufs, U., Busse, O., Kunze, C., Thomalla, G., Nabavi, D.G., Röther, J., Veltkamp, R., Endres, M.
Am Heart J. 2016;172:19-25.

Team

Scientific Staff

  • Dr. med. Wolfgang Böhmerle
  • Dr. med. Dr. phil. Martin Ebinger (Gast)
  • Dr. med. Julius Emmrich
  • Dr. med. Karen Gertz
  • Dr. med. Petra Hühnchen
  • Dr. rer. nat. Friederike Klempin (assoziiert)
  • Samuel Knauss
  • Prof. Dr. med. Golo Kronenberg (Gast)
  • Dr. rer. nat. Nielsen Lagumersindez Denis
  • Dr. med. Thomas Liman
  • Dr. med. Alexander Nave
  • Dr. med. Vincent Prinz (assoziiert)
  • Johanna Schöner
  • Dipl.-Biol. Ph.D. Ria Uhlemann

Students

  • Burcu Ersoy
  • Paul Fischer
  • Antonia van Kampen
  • Stephanie Wegner

Technical Staff

  • Stefanie Balz
  • Renate Franke
  • Bettina Herrmann
  • Melanie Kroh
  • Petra Loge 

Research Fields

  • Post stroke depression
  • Endothelial function in cerebrovascular diseases
  • Inflammation and stroke
  • Cognitive deficits after critical illness
  • Mechanisms of Ischemic Tolerance
  • Neurotoxicology
  • Regeneration after stroke
  • Risk factors
  • Telemedicine
  • Vascular mechanisms of stroke protection
  • Cerebral haemorrhage

Find more details about the research fields on the ExpNeuro website.

Cooperations

International

  • C. Ayata, Boston, USA
  • B.E. Ehrlich, New Haven, USA
  • M.A. Moskowitz, Boston, USA
  • J.C. Baron, Paris, France
  • E. Dejana, Milan, Italy
  • M. Elkind, New York, USA


National

  • M. Götz, Neuherberg/München
  • P.U. Heuschmann, Würzburg
  • G. Kempermann, Dresden
  • U. Laufs, Homburg Saar
  • J. Schulz, Aachen


Berlin Area

  • D. Schmitz, Charité
  • H. Kettenmann, MDC
  • U. Kintscher, Charité
  • P. Vajkoczy, Charité
  • F. Heppner, Charité
  • M. Taupitz, Charité
  • T. Kurth, Charité
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