PD Martin Ebinger, M.D., Ph.D

Research Group Ebinger

PD Martin Ebinger, M.D., Ph.D
Charité, Centrer for Stroke Research Berlin
***Since May 2017, Martin Ebinger has been working as a senior consultant for Medical Park Humboldtmühle in Berlin.***

Profile

Martin Ebinger, an M.D. who also holds a degree in philosophy, started his clinical postgraduate training in Munich, Germany, in the Department of Neurology at the Max Planck Institute for Psychiatry. He continued as a Stroke Fellow at the Royal Melbourne Hospital, Australia, before returning to Germany in 2008 where he took a position at the newly founded CSB Trial Team. He now is a consultant on the general ward, including the lead of the stroke team; he is the lead physician of STEMO. He first authored the publication of the main STEMO results in JAMA in 2014.

List of Publications/Charité Research Data Base   

Selected Publications

Lipoprotein (a) as a risk factor for ischemic stroke: a meta-analysis.
Nave AH, Lange KS, Leonards CO, Siegerink B, Doehner W, Landmesser U, Steinhagen-Thiessen E, Endres M, Ebinger M.
Atherosclerosis. 2015 Oct;242(2):496-503. doi: 10.1016/j.atherosclerosis.2015.08.021.
PMID:26298741

Hyperintense Vessels on FLAIR: Hemodynamic Correlates and Response to Thrombolysis.
Kufner A, Galinovic I, Ambrosi V, Nolte CH, Endres M, Fiebach JB, Ebinger M.
AJNR Am J Neuroradiol. 2015 Aug;36(8):1426-30. doi: 10.3174/ajnr.A4320.
PMID:25977482

Effects of golden hour thrombolysis: a Prehospital Acute Neurological Treatment and Optimization of Medical Care in Stroke (PHANTOM-S) substudy.
Ebinger M, Kunz A, Wendt M, Rozanski M, Winter B, Waldschmidt C, Weber J, Villringer K, Fiebach JB, Audebert HJ.
JAMA Neurol. 2015 Jan;72(1):25-30. doi: 10.1001/jamaneurol.2014.3188.
PMID:25402214

Effect of the use of ambulance-based thrombolysis on time to thrombolysis in acute ischemic stroke: a randomized clinical trial.
Ebinger M, Winter B, Wendt M, Weber JE, Waldschmidt C, Rozanski M, Kunz A, Koch P, Kellner PA, Gierhake D, Villringer K, Fiebach JB, Grittner U, Hartmann A, Mackert BM, Endres M, Audebert HJ; STEMO Consortium.
JAMA. 2014 Apr 23-30;311(16):1622-31. doi: 10.1001/jama.2014.2850.
PMID:24756512

Impetus

No doubt, specialization has been beneficial for scientific advancement. In clinical research, however, the guiding principle should be the patient’s perspective. This perspective changes during the course of stroke, a chronic disease with a long and often hidden medical history, with its sudden onset and long road to recovery. The patient’s perspective guides the Research Group Ebinger in tackling pressing research questions. We start by examining the potential role emerging risk factors, such as triglycerides, may play (the Cream&Sugar study). We speed up ultra-early pre-hospital treatment (STEMO), offer solutions for tricky in-hospital situations (e.g. thrombolysis in wake-up strokes), and we illuminate mechanisms for enhanced rehabilitation measures (biomarkers and MRI studies).

Most Important Project

Protect brain

B_PROUD - Berlin Pre-hospital Or Usual Delivery of stroke care project

The objective of the B_PROUD trial B_PROUD (Berlin Pre-hospital Or Usual Delivery of stroke care project) is to show improved functional outcomes after deployment of the Stroke Emergency Mobile (STEMO) compared to regular care.
More information/project description

Further Projects

Further projects conducted by Martin Ebinger’s research group include 
(1) coordination of the German centers in the EU-funded WAKE-UP trial, comparing the effects of MRI-based thrombolysis to placebo in patients with unknown symptom onset,
(2) the Cream&Sugar study investigating the prognostic value of a combined triglyceride and glucose challenge, and
(3) BAPTISe, a biomarker and MRI study accompanying a randomised controlled trial looking at the effects of physical exercise vs. relaxation sessions during rehabilitation.

Team

  • Moritz Armbrust
  • Peter Brunecker
  • Laura Hanne
  • Peter Harmel
  • Nils Ipsen
  • Anja Kühl
  • Anna Kufner
  • Kristin S. Lange
  • Christopher O. Leonards
  • Sarah Müller
  • Dr. med. Alexander Nave
  • Ludwig Schlemm
  • Leonie Schulz
  • Samantha Taber

Cooperations and Research Partners

  • all other CSB teams
  • all partners of the  WAKE-UP project
  • Hamburg (Götz Thomalla and Christian Gerloff)
  • Homburg (Christian Werner and Ulrich Laufs)
  • Melbourne (Atte Meretoja and Steve M. Davis)
  • Helsinki (Markku Kuisma and Turgut Talisumak)
  • Sevilla (Joan Montaner)
  • Odense (Dorte Gyrd-Hansen and Jan Sørensen)
  • Paris (Guillaume Turc and Marie G. Bousser)
  • Glasgow (Kennedy Lees)
  • Singapore (Deidre De Silva)
  • Berlin (Gerhard W. Meyer, MEYTEC)
  • München (Harald Schneider, LMU, Annina Sorgner GABO:mi)
  • and many more

Education and Teaching

All MDs in Team Ebinger are dedicated teachers at the curriculum of the Charité - Universitätsmedizin Berlin; the Team Ebinger contributes to the "Stroke Unit course for Nurses" and the yearly "Stroke Summer School".

Funding

  • EU
  • BMBF
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