Paper of the Month – 2020
Each month the CSB directors select the paper of the month from the publications of the CSB and the Department of Neurology.
December


Subthalamic stimulation impairs stopping of ongoing movements.
Lofredi R, Auernig GC, Irmen F, Nieweler J, Neumann WJ, Horn A, Schneider GH, Kühn AA.
Brain. 2020 Nov 30:awaa341. doi: 10.1093/brain/awaa341. Online ahead of print.
PMID: 33253351
November


Endothelial and leukocyte-derived microvesicles and cardiovascular risk after stroke-PROSCIS-B
Huo S, Kränkel N, Nave AH, Sperber PS, Rohmann JL, Piper SK, Heuschmann P, Landmesser U, Endres M, Siegerink B, Liman TGG. Neurology. 2020 Nov 12:10.1212/WNL.0000000000011223. doi: 10.1212/WNL.0000000000011223. Online ahead of print. PMID: 33184230
Oktober



Association Between Thrombus Perviousness Assessed on Computed Tomography and Stroke Cause.
Kufner A, Erdur H, Endres M, Nolte CH, Scheel M, Schlemm L.
Stroke. 2020 Oct 1:STROKEAHA120031148. doi: 10.1161/STROKEAHA.120.031148. Online ahead of print.
PMID: 32998650
More about the article and the authors
PubMed
September



A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model
Kreye J*, Reincke SM*, Kornau HC, Sánchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Höltje M, Dietert K, Stöffler L, Wardenburg Nv, Hoof Sv, Homeyer MA, Hoffmann J, Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Prüss H.
Cell. 2020 DOI: doi.org/10.1016/j.cell.2020.09.049
*equal contribution
August


A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder.
Li N, Baldermann JC, Kibleur A, Treu S, Akram H, Elias GJB, Boutet A, Lozano AM, Al-Fatly B, Strange B, Barcia JA, Zrinzo L, Joyce E, Chabardes S, Visser-Vandewalle V, Polosan M, Kuhn J, Kühn AA, Horn A.
Nat Commun. 2020 Jul 3;11(1):3364. doi: 10.1038/s41467-020-16734-3.
PMID: 32620886
More about the article and the author
PubMed
July


Hypoxic-Ischemic Encephalopathy Evaluated by Brain Autopsy and Neuroprognostication After Cardiac Arrest.
Endisch C, Westhall E, Kenda M, Streitberger KJ, Kirkegaard H, Stenzel W, Storm C, Ploner CJ, Cronberg T, Friberg H, Englund E, Leithner C.
JAMA Neurol. 2020 Jul 20:e202340. doi: 10.1001/jamaneurol.2020.2340. Online ahead of print.
PMID: 32687592
More about the article and the author
PubMed
June


Obesity and Weight Loss Are Inversely Related to Mortality and Cardiovascular Outcome in Prediabetes and Type 2 Diabetes: Data From the ORIGIN Trial.
Doehner W, Gerstein HC, Ried J, Jung H, Asbrand C, Hess S, Anker SD.
Eur Heart J. 2020 May 13:ehaa293. doi: 10.1093/eurheartj/ehaa293. Online ahead of print.
PMID: 32402060
More about the article and the author
PubMed
May


Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis.
Abrahamyan S, Eberspächer B, Hoshi MM, Aly L, Luessi F, Groppa S, Klotz L, Meuth SG, Schroeder C, Grüter T, Tackenberg B, Paul F, Then-Bergh F, Kümpfel T, Weber F, Stangel M, Bayas A, Wildemann B, Heesen C, Zettl U, Warnke C, Antony G, Hessler N, Wiendl H, Bittner S, Hemmer B, Gold R, Salmen A, Ruprecht K; German Competence Network Multiple Sclerosis (KKNMS); Other members of the KKNMS that acted as collaborators in this study.
J Neurol Neurosurg Psychiatry. 2020 May 5:jnnp-2020-322941. doi: 10.1136/jnnp-2020-322941. Online ahead of print.
PMID: 32371533
More about the article and the author
PubMed
April


Symptomatic pharmacotherapy in ALS: data analysis from a platformbased medication management programme.
Meyer T, Kettemann D, Maier A, Grehl T, Weyen U, Grosskreutz J, Steinbach R, Norden J, George A,Hermann A, Guenther R, Petri S, Schreiber-Katz O, Dorst J, Ludolph AC, Walter B, Münch C, Spittel S.
J Neurol Neurosurg Psychiatry. 2020 Apr 21. pii: jnnp-2020-322938. doi: 10.1136/jnnp-2020-322938. [Epub ahead of print]
PMID: 32317400
More about the article and the author
PubMed
March



Complement deposition at the neuromuscular junction in seronegative myasthenia gravis.
Hoffmann S, Harms L, Schuelke M, Rückert JC, Goebel HH, Stenzel W, Meisel A.
Acta Neuropathol. 2020 Mar 10. doi: 10.1007/s00401-020-02147-5. [Epub ahead of print]
PMID: 32157386
More about the article and the author
PubMed
February




Association Between High-Sensitivity Cardiac Troponin and Risk of Stroke in 96 702 Individuals: A Meta-Analysis.
Broersen LHA, Stengl H, Nolte CH, Westermann D, Endres M, Siegerink B, Scheitz JF.
Stroke. 2020 Feb 10:STROKEAHA119028323. doi: 10.1161/STROKEAHA.119.028323. [Epub ahead of print]
PMID: 32078461
More about the article and the author
PubMed
January



Blockade of IL-6 signaling prevents paclitaxel-induced neuropathy in C57Bl/6 mice.
Huehnchen P, Muenzfeld H, Boehmerle W, Endres M.
Cell Death Dis. 2020 Jan 22;11(1):45. doi: 10.1038/s41419-020-2239-0.
PMID: 31969555