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Paper of the Month 12/2020

Subthalamic stimulation impairs stopping of ongoing movements.

Lofredi R, Auernig GC, Irmen F, Nieweler J, Neumann WJ, Horn A, Schneider GH, Kühn AA.
Brain. 2020 Nov 30:awaa341. doi: 10.1093/brain/awaa341. Online ahead of print.
PMID: 33253351

Paper of the Month 11/2020

Endothelial and leukocyte-derived microvesicles and cardiovascular risk after stroke-PROSCIS-B

Huo S, Kränkel N, Nave AH, Sperber PS, Rohmann JL, Piper SK, Heuschmann P, Landmesser U, Endres M, Siegerink B, Liman TGG.
Neurology. 2020 Nov 12:10.1212/WNL.0000000000011223. doi: 10.1212/WNL.0000000000011223. Online ahead of print.
PMID: 33184230

Paper of the Month 10/2020

Association Between Thrombus Perviousness Assessed on Computed Tomography and Stroke Cause

Kufner A, Erdur H, Endres M, Nolte CH, Scheel M, Schlemm L. Stroke. 2020 Oct 1:STROKEAHA120031148. doi: 10.1161/STROKEAHA.120.031148. Online ahead of print.
PMID: 32998650  

Paper of the Month 09/2020

A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model.

Kreye J*, Reincke SM*, Kornau HC, Sánchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Höltje M, Dietert K, Stöffler L, Wardenburg Nv, Hoof Sv, Homeyer MA, Hoffmann J,  Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Prüss H.

Cell. 2020 DOI: doi.org/10.1016/j.cell.2020.09.049

Paper of the Month 08/2020

A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder.

Li N, Baldermann JC, Kibleur A, Treu S, Akram H, Elias GJB, Boutet A, Lozano AM, Al-Fatly B, Strange B, Barcia JA, Zrinzo L, Joyce E, Chabardes S, Visser-Vandewalle V, Polosan M, Kuhn J, Kühn AA, Horn A.
Nat Commun. 2020 Jul 3;11(1):3364. doi: 10.1038/s41467-020-16734-3.
PMID: 32620886

Paper of the Month 07/2020

Hypoxic-Ischemic Encephalopathy Evaluated by Brain Autopsy and Neuroprognostication After Cardiac Arrest.

Endisch C, Westhall E, Kenda M, Streitberger KJ, Kirkegaard H, Stenzel W, Storm C, Ploner CJ, Cronberg T, Friberg H, Englund E, Leithner C.
JAMA Neurol. 2020 Jul 20:e202340. doi: 10.1001/jamaneurol.2020.2340. Online ahead of print.
PMID: 32687592

Paper of the Month 06/2020

Obesity and Weight Loss Are Inversely Related to Mortality and Cardiovascular Outcome in Prediabetes and Type 2 Diabetes: Data From the ORIGIN Trial.

Doehner W, Gerstein HC, Ried J, Jung H, Asbrand C, Hess S, Anker SD.
Eur Heart J. 2020 May 13:ehaa293. doi: 10.1093/eurheartj/ehaa293. Online ahead of print.
PMID: 32402060

Paper of the Month 05/2020

Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis.

Abrahamyan S, Eberspächer B, Hoshi MM, Aly L, Luessi F, Groppa S, Klotz L, Meuth SG, Schroeder C, Grüter T, Tackenberg B, Paul F, Then-Bergh F, Kümpfel T, Weber F, Stangel M, Bayas A, Wildemann B, Heesen C, Zettl U, Warnke C, Antony G, Hessler N, Wiendl H, Bittner S, Hemmer B, Gold R, Salmen A, Ruprecht K; German Competence Network Multiple Sclerosis (KKNMS); Other members of the KKNMS that acted as collaborators in this study.
J Neurol Neurosurg Psychiatry. 2020 May 5:jnnp-2020-322941. doi: 10.1136/jnnp-2020-322941. Online ahead of print.
PMID: 32371533

Paper of the Month 04/2020

Symptomatic pharmacotherapy in ALS: data analysis from a platformbased medication management programme.

Meyer T, Kettemann D, Maier A, Grehl T, Weyen U, Grosskreutz J, Steinbach R, Norden J, George A,Hermann A, Guenther R, Petri S, Schreiber-Katz O, Dorst J, Ludolph AC, Walter B, Münch C, Spittel S.
J Neurol Neurosurg Psychiatry. 2020 Apr 21. pii: jnnp-2020-322938. doi: 10.1136/jnnp-2020-322938. [Epub ahead of print]
PMID: 32317400

Paper of the Month 03/2020

Complement deposition at the neuromuscular junction in seronegative myasthenia gravis

Hoffmann S, Harms L, Schuelke M, Rückert JC, Goebel HH, Stenzel W, Meisel A.
Acta Neuropathol. 2020 Mar 10. doi: 10.1007/s00401-020-02147-5. [Epub ahead of print]
PMID: 32157386